Discover the Difference, Make it a Reality

Examining and getting a firm understanding of your compound’s characteristics early on is a vital first step in a successful development process. Our scientists combine decades of drug pre-formulation development expertise with an extensive understanding of commercial pharmaceutical manufacturing processes to help you develop and commercialize pharmaceutical products in non-sterile and sterile semi-solid and liquid dosage forms.

Pre-formulation Services

  • Raw material sourcing
  • Solubility profile (in buffers and non-aqueous solvents) and partition coefficient of the active pharmaceutical ingredient (API)
  • API compatibility with excipients
  • Stability of API and factors affecting stability (including heat, light and pH)
  • Method development and method transfer for particle size of wet and dry particles by laser diffraction (for both API and the formulation)
  • API characterization by differential scanning calorimetry (DSC), powder x-ray diffraction, fourier transform infrared (FTIR) spectroscopy and particle morphology by optical microscopy
  • Formulation and packaging compatibility
  • Surface tension of aqueous and non-aqueous liquids