Drug Development and Analytical Testing Services for Nasal Sprays and Pressurized Metered-Dose Inhalers

In addition to DPT's comprehensive drug development capabilities, we provide expertise for developing, testing, and manufacturing nasal sprays and pressurized metered-dose inhalers.

Category Examples

• Rx and OTC
• Small and large molecule
• Preserved, preservative-free, and sterile nasal formulations
• Unit-dose, bi-dose and multi-dose nasal sprays
• Pressurized metered-dose inhalers
• Controlled substances Schedules II-V

Specialized drug development and analytical testing services for nasal sprays, inhaled products, and pressurized metered-dose inhalers include:

• Package identification, specification, and validation
• Clinical trial material manufacturing
• Device robustness
• Spray pattern
• Plume geometry
• Spray content uniformity
• Droplet size (laser diffraction)
• Tail-off characteristics
• Priming and repriming
• Repriming/effect of resting time
• Effect of dosing orientation on spray content uniformity and droplet size
• CMC module preparation, review, and support
• Other